Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487379 | 1.00 | LMNA (0.72) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL7365408 | 0.88 | LMNA (0.68) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL7365405 | 0.88 | LMNA (0.68) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL11321330 | 0.88 | LMNA (0.68) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL25279841 | 0.86 | SMN1; SMN2 (0.77) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL2579539 | 0.86 | LMNA (0.72) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL10958215 | 0.85 | LMNA (0.73) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL10958217 | 0.85 | LMNA (0.73) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL5462606 | 0.84 | LMNA (0.64) | LMNAMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL5462612 | 0.84 | LMNA (0.64) | LMNAMEN1KMT2AUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720848-B1 | DERIVATIVES OF ALKYLPIPERAZINE- AND ALKYLHOMOPIPERAZINE- CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2007-12-05 | — | — | EP | disclosed |