⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29033708 | 0.84 | — | — | |
| Hydrochlorthiazide SCHEMBL29780358 | 0.82 | — | — | |
| Iodide SCHEMBL29033692 | 0.81 | MEN1 (0.30) | — | |
| SCHEMBL5015374 | 0.78 | TSHR (0.34) | — | |
| Bromide SCHEMBL2945638 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL6936140 | 0.76 | — | — | |
| SCHEMBL6936019 | 0.75 | ALDH1A1 (0.31) | — | |
| Iodide SCHEMBL926373 | 0.74 | — | — | |
| Bromide SCHEMBL3844692 | 0.74 | ALDH1A1 (0.31) | — | |
| Bromide SCHEMBL29033694 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906235-B1 | METHOD FOR PREPARING SULFONAMIDES DRUGS | ASCENTAGE PHARMA SUZHOU CO LTD (CN) | 2023-03-15 | — | — | EP | claimed |
| CN-113563317-A | Synthesis method of tocopherol nicotinate | 上海克琴科技有限公司 | 2021-10-29 | — | — | CN | claimed |
| EP-2195289-B1 | PYRROLE COMPOUNDS AS INHIBITORS OF MYCOBACTERIA, SYNTHESIS THEREOF ANS INTERMEDIATES THERETO | UNIV ROMA (IT) | 2013-06-19 | — | — | EP | claimed |
| EP-1948598-B1 | PROCESS FOR PREPARATION OF (3R, 5R)-7-[2-(4-FLUOROPHENYL)-5-ISOPROPYL-3-PHENYL-4-[(4-HYDROXY METHYL PHENYL AMINO) CARBONYL]-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID HEMI CALCIUM SALT | RANBAXY LAB LTD (IN) | 2013-01-09 | — | — | EP | claimed |
| CN-101304967-B | Preparation method of (3R,5R) -7- [2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- [ (4-hydroxymethyl phenylamino) carbonyl ] -pyrrole-1-yl ] -3, 5-dihydroxy-heptanoic acid hemicalcium salt | RANBAXY LAB LTD | 2011-10-05 | — | — | CN | claimed |
| CN-101304967-A | Preparation method of (3R,5R) -7- [ 2- (4-fluorophenyl) -5-isopropyl-3-phenyl-4- [ (4-hydroxymethyl phenylamino) carbonyl ] -pyrrole-1-yl ] -3, 5-dihydroxy-heptanoic acid hemicalcium salt | RANBAXY LAB LTD (IN) | 2008-11-12 | — | — | CN | claimed |
| EP-1866283-A2 | 4-FLUOROPHENYL-DERIVATIVES OF 1-{[1,5 -BIS (4-CHLOROPHENYL) -2-METHYL-1H-PYRROL-3-YL]METHYL} -4- METHYLPIPERAZINE, SYNTHESIS PROCESS AND USES THEREOF | Universita' Degli Studi di Siena (IT) | 2007-12-19 | — | — | EP | claimed |
| CN-101084235-A | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS INC (US) | 2007-12-05 | — | — | CN | claimed |
| CN-1980890-A | Process for the preparation of atorvastatin | RANBAXY LAB LTD (IN) | 2007-06-13 | — | — | CN | claimed |
| WO-2006092822-A2 | 4-FLUOROPHENYL-DERIVATIVES OF 1-{[1,5 -BIS (4-CHLORO PHENYL) -2-METHYL-1H-PYRROL-3-YL]METHYL} -4- METHYLPI PΕRAZINE, SYNTHESIS PROCESS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2006-09-08 | — | — | WO | claimed |
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0615854-B1 | Recording sheets containing cationic sulphur compounds | XEROX CORP (US) | 1997-06-04 | — | — | EP | claimed |
| EP-0402151-B1 | New 2, 5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO INC (US) | 1996-02-07 | — | — | EP | claimed |
| EP-0330172-B1 | Improved process for trans-6-[2-(substituted-pyrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | WARNER LAMBERT CO (US) | 1994-08-10 | — | — | EP | claimed |
| EP-0244717-A2 | Process for the preparation of 2,3-epoxyamides | BAYER AG (DE) | 1987-11-11 | — | — | EP | claimed |
| JP-10195071-A | — | — | None | — | — | JP | disclosed |
| EP-0244717-A2 | Process for the preparation of 2,3-epoxyamides | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |