SCHEMBL54877

SCHEMBL54877

CCOC(=O)CC(=O)CCl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.64
MGAM O43451 1/20 0.64
SI P14410 1/20 0.64
MGAM2 Q2M2H8 1/20 0.64
ALDH1A1 P00352 5/20 0.46
TRPA1 O75762 1/20 0.46
HSD17B10 Q99714 2/20 0.46
LMNA P02545 1/20 0.46
FAAH O00519 2/20 0.44
CYP1A2 P05177 1/20 0.40
HTT P42858 2/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALOX15 P16050 2/20 0.39
PKM P14618 1/20 0.39
SOAT1 P35610 1/20 0.39
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30381316 0.98 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL28359032 0.98 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
Formaldehyde SCHEMBL459758 0.96 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL4983773 0.96 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
Trimethylammonium SCHEMBL10940613 0.94 GAA (0.56) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7729694 0.94 GAA (0.56) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL28539237 0.92 GAA (0.54) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL20706490 0.88 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL18855613 0.85 GAA (0.47) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL155563 0.85 GAA (0.78) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4048 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105133-A1 TNF- Α AND IL-17 INHIBITOR COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES DAMLE LATHA (IN) 2026-05-21 WO claimed
US-20260085334-A1 ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) 2026-03-26 US claimed
CN-120192281-A Febuxostat Process for the preparation of intermediates 潍坊市海欣药业有限公司 2025-06-24 CN claimed
CN-119899194-B Bicyclic heteroaryl BRAF negative allosteric modulator, and preparation method and application thereof 浙江省人民医院 2025-06-24 CN claimed
CN-116675306-B Decoloring auxiliary agent for treating phenol-containing wastewater activated carbon as well as preparation method and application thereof 浙江鸿盛化工有限公司 2025-06-24 CN claimed
CN-116199591-B Industrial preparation method of levocarnitine 山东齐都药业有限公司 2025-06-03 CN claimed
EP-4551693-A1 ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) 2025-05-14 EP claimed
CN-119899194-A Bicyclic heteroaryl BRAF negative allosteric modulator, and preparation method and application thereof 浙江省人民医院 2025-04-29 CN claimed
CN-119591966-B Multilayer co-extrusion cosmetic pipe and preparation method thereof 安徽紫金新材料科技股份有限公司 2025-04-25 CN claimed
US-12281348-B2 Method for the continuous flow synthesis of (R)-4-halo-3-hydroxy-butyrate FUDAN UNIVERSITY (CN) 2025-04-22 US claimed
EP-0955375-A2 Method for producing optically active 4-Halo-3-hydroxybutyric acid ester DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-11-10 EP claimed
EP-0573999-B1 Process for preparation of alkyltetronates LONZA AG (CH) 1998-08-26 EP claimed
US-5700670-A TREATING MICROORGANISM CULTURE WITH ALKYL ESTER OF GAMMA-SUBSTITUTED ACETOACETIC ACID FOR STEREOSPECIFIC REDUCTION OF CARBONYL GROUP TO HYDROXYL GROUP YIELDS GAMMA-SUBSTITUTED 3-HYDROXYBUTYRIC ACID MITSUBISHI CHEMICAL CORPORATION (JP) 1997-12-23 US claimed
EP-0737751-A2 Method for producing optically active ester of gamma-substituted-beta-hydroxybutyric acid Mitsubishi Chemical Corporation (JP) 1996-10-16 EP claimed
US-5310947-A Process for the production of tetronic acid alkyl esters LONZA LTD. (CH) 1994-05-10 US claimed
EP-0237028-A1 N-(phenyl) or n-(phenylcyclopropyl)-2,5-dihydro-2-oxo-4, (substituted phenyl) amino-3-furancarboxamide derivatives PENNWALT CORPORATION (US) 1987-09-16 EP claimed
CN-85109254-A The sunlight chlorization technology of synthesizing coumaphos by use 1987-06-24 CN claimed
US-4473508-A Process for the production of γ-chloroacetoacetic acid chloride LONZA LTD. (CH) 1984-09-25 US claimed
US-4443627-A Process for the production of carnitine amide LONZA LTD. (CH) 1984-04-17 US claimed
US-4414400-A FROM 4-HALOACETOACETIC ESTER, CYCLIZING ETHER CLEAVAGE OF 4-TERT-BUTOXYACETOACETIC ESTER LONZA LTD. (CH) 1983-11-08 US claimed