SCHEMBL5487774

SCHEMBL5487774

[O]c1ccccc1OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
USP2 O75604 2/20 0.51
TSHR P16473 1/20 0.51
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2C9 P11712 1/20 0.43
RECQL P46063 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.36
HPGD P15428 3/20 0.36
XBP1 P17861 2/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HTT P42858 2/20 0.36
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5491457 0.86 USP2 (0.40) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL23054263 0.76 CYP1A2 (0.47) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL1710062 0.76 CYP1A2 (0.47) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL750567 0.75 CYP1A2 (0.41) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL25790289 0.74 ALDH1A1 (0.48) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL3655004 0.73 MAPT (0.44) MAPTUSP2CYP1A2CYP2C9L3MBTL1
SCHEMBL14522583 0.73 CYP1A2 (0.41) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL24031074 0.72 TSHR (0.53) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL5488003 0.72 USP2 (0.47) MAPTUSP2TSHRCYP1A2CYP2C19
SCHEMBL3187742 0.71 CYP1A2 (0.50) MAPTUSP2TSHRCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7201950-B2 Optical compensatory sheet, elliptical polarizing plates and liquid-crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-10 US disclosed
US-20040234706-A1 Optical compensatory sheet, elliptical polarizing plates and liquid-crystal display FUJI PHOTO FILM CO., LTD. (JP) 2004-11-25 US disclosed