Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.68 |
| ▸ | TSHR | P16473 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.68 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecylamine SCHEMBL133142 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Decylamine SCHEMBL3405270 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL18783128 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Octadecylamine SCHEMBL9784638 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Tetradecylamine SCHEMBL609941 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Dodecylamine SCHEMBL167181 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Hexadecylamine SCHEMBL325395 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Icosylamine SCHEMBL5495670 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Octadecylamine SCHEMBL11524045 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL10891812 | 1.00 | DNM1 (0.68) | DNM1TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4740420-A | WATER-SOLUBLE METAL SALT WITH THE ION VALENCE OF METAL BEING 2 TO 4 AND CATIONIC ORGANIC MATERIAL | RICOH COMPANY, LTD. (JP) | 1988-04-26 | — | — | US | claimed |
| US-4680235-A | Recording material for ink jet printing | RICOH COMPANY, LTD. (JP) | 1987-07-14 | — | — | US | claimed |
| US-4554555-A | Recording method by use of inks | RICOH COMPANY, LTD. (JP) | 1985-11-19 | — | — | US | claimed |
| CN-111566083-A | Novel glutamine antagonists and uses thereof | 约翰·霍普金斯大学 | 2020-08-21 | — | — | CN | disclosed |
| CN-110520118-A | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS | 2019-11-29 | — | — | CN | disclosed |
| US-7169444-B2 | Method for treating surface of ink jet recording medium having recorded image | SEIKO EPSON CORPORATION (JP) | 2007-01-30 | — | — | US | disclosed |
| US-20030005945-A1 | Method for surface-treatment, surface-treated article and device for surface treatment | SEIKO EPSON CORPORATION (JP) | 2003-01-09 | — | — | US | disclosed |
| EP-1186439-A1 | METHOD FOR SURFACE TREATMENT, SURFACE-TREATED ARTICLE AND DEVICE FOR SURFACE TREATMENT | SEIKO EPSON CORPORATION (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-5320902-A | Suitable for use in ink jet printing | XEROX CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |
| US-4740420-A | WATER-SOLUBLE METAL SALT WITH THE ION VALENCE OF METAL BEING 2 TO 4 AND CATIONIC ORGANIC MATERIAL | RICOH COMPANY, LTD. (JP) | 1988-04-26 | — | — | US | disclosed |
| US-4680235-A | Recording material for ink jet printing | RICOH COMPANY, LTD. (JP) | 1987-07-14 | — | — | US | disclosed |
| US-4554555-A | Recording method by use of inks | RICOH COMPANY, LTD. (JP) | 1985-11-19 | — | — | US | disclosed |
| US-4126475-A | LIME AND OXIDES OR SILICATES OF IRON AND ALUMINUM | HANSEN TORBEN C | 1978-11-21 | — | — | US | disclosed |
| US-4012351-A | CATIONIC SURFACTANT | AMCHEM PRODUCTS, INC. (US) | 1977-03-15 | — | — | US | disclosed |