SCHEMBL5488007

SCHEMBL5488007

C=Cc1c(F)c(F)c([Si](OC)(OC)OC)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30107691 0.81
SCHEMBL3135744 0.79
SCHEMBL16466661 0.75 HSD17B10 (0.32)
SCHEMBL22116259 0.73
SCHEMBL7604250 0.72
SCHEMBL14468295 0.71 HSD17B10 (0.31)
SCHEMBL13429599 0.70
SCHEMBL3136670 0.70
SCHEMBL85510 0.69 VCP (0.32)
SCHEMBL8979429 0.67 VCP (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
EP-1318153-B1 Process for the preparation of styrylsilanes FRAUNHOFER GES FORSCHUNG (DE) 2004-08-04 EP disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed
EP-1318153-A1 Process for the preparation of styrylsilanes Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2003-06-11 EP disclosed