Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485621 | 0.78 | MAOB (0.35) | SLC6A4SLC6A3SLC6A2HSD11B1 | |
| SCHEMBL5484135 | 0.75 | SLC6A4 (0.40) | KDM1ASLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL28104907 | 0.66 | KDM1A (0.50) | KDM1ASLC6A4SLC6A3SLC6A2PSEN1 | |
| SCHEMBL4320028 | 0.66 | KDM1A (0.55) | KDM1ASLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL30344739 | 0.66 | KDM1A (0.55) | KDM1ASLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL23232239 | 0.66 | OPRL1 (0.59) | KDM1ASLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL17033038 | 0.66 | KDM1A (0.50) | KDM1ASLC6A4SLC6A3SLC6A2PSEN1 | |
| SCHEMBL27173081 | 0.66 | KDM1A (0.50) | KDM1ASLC6A4SLC6A3SLC6A2PSEN1 | |
| SCHEMBL19191795 | 0.66 | SLC6A4 (0.42) | KDM1ASLC6A4SLC6A3SLC6A2PSEN1 | |
| SCHEMBL17031730 | 0.66 | KDM1A (0.46) | KDM1ASLC6A4SLC6A3SLC6A2PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |