Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494541 | 0.82 | OPRM1 (0.36) | SLC6A4SLC6A3SLC6A2OPRM1HSD11B1 | |
| SCHEMBL5488074 | 0.75 | KDM1A (0.42) | SLC6A4SLC6A3SLC6A2KDM1AHTR2A | |
| SCHEMBL19273962 | 0.66 | SLC6A4 (0.57) | SLC6A4SLC6A3SLC6A2KDM1AHTR2A | |
| SCHEMBL19193456 | 0.64 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2KDM1AHTR2A | |
| SCHEMBL30477031 | 0.64 | LMNA (0.58) | SLC6A4OPRM1LMNATSHRNPSR1 | |
| SCHEMBL17033038 | 0.63 | KDM1A (0.50) | SLC6A4SLC6A3SLC6A2KDM1AHTR2A | |
| SCHEMBL15735907 | 0.63 | ACHE (0.39) | LMNA | |
| SCHEMBL19191795 | 0.63 | SLC6A4 (0.42) | SLC6A4SLC6A3SLC6A2KDM1AHTR2A | |
| Ammonia Solution, Strong SCHEMBL28903694 | 0.62 | KDM1A (0.48) | SLC6A4SLC6A3SLC6A2KDM1AHTR2A | |
| SCHEMBL15736416 | 0.62 | ACHE (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |