SCHEMBL5488204

SCHEMBL5488204

CCCC(O)c1ccc(OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.58
GAA P10253 1/20 0.54
ALDH1A1 P00352 2/20 0.50
MAPT P10636 1/20 0.50
HTR1A P08908 3/20 0.49
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
ADRB2 P07550 2/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
NR1I2 O75469 1/20 0.44
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6055130 0.90 AOC3 (0.56) AOC3GAAALDH1A1MAPTHTR1A
SCHEMBL31287488 0.89 AOC3 (0.54) AOC3GAAALDH1A1MAPTHTR1A
SCHEMBL2829738 0.87 AOC3 (0.53) AOC3GAAALDH1A1MAPTHTR1A
SCHEMBL28446300 0.87 AOC3 (0.53) AOC3GAAALDH1A1MAPTHTR1A
SCHEMBL19391564 0.87 AOC3 (0.53) AOC3GAAALDH1A1MAPTHTR1A
SCHEMBL10327515 0.87 AOC3 (0.53) AOC3GAAALDH1A1MAPTHTR1A
SCHEMBL6478106 0.87 AOC3 (0.53) AOC3GAAALDH1A1MAPTHTR1A
SCHEMBL21633858 0.85 LMNA (0.48) AOC3ALDH1A1HTR1APDE4APDE4B
SCHEMBL9245675 0.84 GAA (0.58) AOC3GAAALDH1A1MAPTHTR1A
SCHEMBL4450372 0.84 GAA (0.58) AOC3GAAALDH1A1MAPTHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117751155-A Copolymerization of aldehydes and vinyl ethers 巴斯夫欧洲公司 2024-03-22 CN disclosed
CN-117440986-A Polyisobutene having a high content of specific double bond isomers 巴斯夫欧洲公司 2024-01-23 CN disclosed
CN-113698514-B Process for preparing highly reactive isobutylene homo-or copolymers 巴斯夫欧洲公司 2023-11-10 CN disclosed
CN-116075531-A Process for preparing highly reactive isobutylene homo-or copolymers 巴斯夫欧洲公司 2023-05-05 CN disclosed
CN-108602913-B Method for producing highly reactive isobutene homo-or copolymers 巴斯夫欧洲公司 2022-07-08 CN disclosed
CN-113698514-A Method for producing highly reactive isobutene homo-or copolymers 巴斯夫欧洲公司 2021-11-26 CN disclosed
CN-109415452-B Method for producing highly reactive isobutene homo-or copolymers 巴斯夫欧洲公司 2021-10-26 CN disclosed
CN-108602914-B Method for producing highly reactive isobutene homo-or copolymers 巴斯夫欧洲公司 2021-09-24 CN disclosed
CN-112321440-B Amino phenyl ketone compound and preparation method and application thereof 南方医科大学 2021-09-24 CN disclosed
CN-112321440-A Amino phenyl ketone compound and preparation method and application thereof 南方医科大学 2021-02-05 CN disclosed
EP-1300381-A1 Process for preparing optically active alcohols Japan Science and Technology Corporation (JP) 2003-04-09 EP disclosed
US-6544976-B1 Treating disorders characterized by neuronal damage caused by disease or trauma, such as Parkinson's disease, Alzheimer's disease, stroke, multiple sclerosis, amyotrophic lateral sclerosis, diabetic neuropathy and Bell's palsy. ORTHO-MCNEIL PHARMACEUTICAL, INC. 2003-04-08 US disclosed
EP-1235776-A1 TRIPHENYLALKENE DERIVATIVES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS Hormos Medical Corporation (FI) 2002-09-04 EP disclosed
EP-1107944-A1 AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-06-20 EP disclosed
WO-2001036360-A1 TRIPHENYLALKENE DERIVATIVES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS HORMOS MEDICAL CORPORATION (FI) 2001-05-25 WO disclosed
US-6184381-B1 USEFUL AS INTERMEDIATES FOR SYNTHESIZING PHARMACEUTICAL CHEMICALS, LIQUID CRYSTAL MATERIALS AND AGENTS FOR OPTICAL RESOLUTION, REDUCTION, KETONES TO ALCOHOL, IMINES TO AMINES JAPAN SCIENCE & TECHNOLOGY CORP. (JP) 2001-02-06 US disclosed
WO-2001004091-A1 NEUROTROPHIC 2-AZETIDINECARBOXYLIC ACID DERIVATIVES, AND RELATED COMPOSITIONS AND METHODS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-01-18 WO disclosed
WO-2000012462-A1 AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-03-09 WO disclosed
EP-0916637-A1 PROCESS FOR PREPARATING OPTICALLY ACTIVE COMPOUNDS Japan Science and Technology Corporation (JP) 1999-05-19 EP disclosed
US-5126375-A Asthma, chronic bronchitis GLAXO GROUP LTD. (GB) 1992-06-30 US disclosed