Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylstilbestrol Diphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 known ✓ | Q92731 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylstilbestrol Diphosphate SCHEMBL2496868 | 0.88 | BLM (0.96) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| Diethylstilbestrol Diphosphate SCHEMBL809597 | 0.88 | BLM (0.96) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| Diethylstilbestrol Diphosphate SCHEMBL9370 | 0.86 | BLM (1.00) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| Diethylstilbestrol Diphosphate SCHEMBL6231203 | 0.86 | BLM (1.00) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| Diethylstilbestrol Diphosphate SCHEMBL3664191 | 0.83 | BLM (0.93) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| SCHEMBL707840 | 0.80 | BLM (0.87) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| SCHEMBL707841 | 0.80 | BLM (0.87) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| Diethylstilbestrol Diphosphate SCHEMBL7617243 | 0.80 | BLM (0.87) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| SCHEMBL14608595 | 0.78 | BLM (0.81) | BLMESR1SMN1; SMN2KMT2AHIF1A | |
| Diethylstilbestrol Diphosphate SCHEMBL8937910 | 0.73 | BLM (0.72) | BLMESR1SMN1; SMN2KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |