Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tipredane SCHEMBL10881217 | 1.00 | HIF1A (0.59) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| Tipredane SCHEMBL120921 | 1.00 | HIF1A (0.59) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| Tipredane SCHEMBL9569097 | 1.00 | HIF1A (0.59) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| Tipredane SCHEMBL10881220 | 1.00 | HIF1A (0.59) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| Tipredane SCHEMBL9569094 | 1.00 | HIF1A (0.59) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| Tipredane SCHEMBL9569099 | 1.00 | HIF1A (0.59) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| SCHEMBL11211400 | 0.95 | HIF1A (0.61) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| SCHEMBL11211398 | 0.95 | HIF1A (0.61) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| SCHEMBL11198668 | 0.94 | HIF1A (0.58) | HIF1ACYP3A4LMNAALDH1A1NR3C1 | |
| SCHEMBL10880778 | 0.94 | HIF1A (0.58) | HIF1ACYP3A4LMNAALDH1A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021360-A1 | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase | EPIGENESIS PHARMACEUTICALS, LLC | 2007-01-25 | — | — | US | claimed |
| EP-0073026-B1 | 17,17-BIS(SUBSTITUTED THIO)-3-KETOANDROSTENES AND PHARMACEUTICAL COMPOSITIONS | E.R. Squibb & Sons, Inc. (US) | 1986-03-19 | — | — | EP | claimed |
| EP-0524813-A1 | Selective thioketalization process, process for preparing thioenol ethers from thioketals, and process for the preparation of thioketals | E.R. SQUIBB & SONS, INC. (US) | 1993-01-27 | — | — | EP | disclosed |
| EP-0316834-B1 | STEROID CREAM FORMULATION | E.R. Squibb & Sons, Inc. (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0316815-B1 | STEROID OINTMENT FORMULATION | E.R. Squibb & Sons, Inc. (US) | 1992-05-27 | — | — | EP | disclosed |
| US-4883792-A | ANTIFUNGAL CREAM CONTAINING TIPREDANE | E.R. SQUIBB & SONS, INC., A DE CORP. | 1989-11-28 | — | — | US | disclosed |
| US-4868170-A | ANTIINFLAMMATORY, OXIDATION RESISTANCE | E. R. SQUIBB & SONS, INC. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4868169-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0316834-A1 | Steroid cream formulation | E.R. Squibb & Sons, Inc. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0316815-A1 | Steroid ointment formulation | E.R. Squibb & Sons, Inc. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0316815-A1 | Steroid ointment formulation | E.R. Squibb & Sons, Inc. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0105224-B1 | ANDROSTENES AND PROCESS FOR THEIR PREPARATION | E.R. Squibb & Sons, Inc. (US) | 1987-01-21 | — | — | EP | disclosed |
| EP-0073026-B1 | 17,17-BIS(SUBSTITUTED THIO)-3-KETOANDROSTENES AND PHARMACEUTICAL COMPOSITIONS | E.R. Squibb & Sons, Inc. (US) | 1986-03-19 | — | — | EP | disclosed |
| US-4446071-A | Intermediates useful in the preparation of 17,17-bis(substituted thio) androstenes | E. R. SQUIBB & SONS, INC. (US) | 1984-05-01 | — | — | US | disclosed |
| EP-0105224-A2 | Androstenes and process for their preparation | E.R. Squibb & Sons, Inc. (US) | 1984-04-11 | — | — | EP | disclosed |
| US-4435326-A | Intermediates useful in the preparation of 17,17-bis(substituted thio)androstenes | E. R. SQUIBB & SONS, INC. (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0073026-A1 | 17,17-Bis(substituted thio)-3-ketoandrostenes and pharmaceutical compositions | E.R. Squibb & Sons, Inc. (US) | 1983-03-02 | — | — | EP | disclosed |
| US-4361559-A | TOPICAL ADMINISTRATION FOR SKIN DISORDERS OF ASTHMA | E. R. SQUIBB & SONS, INC. (US) | 1982-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021360-A1 | Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase | RECQL, GSS, DDX17 | HIF1A 1076/4885CYP3A4 2529/4885LMNA 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.