Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | GALR3 | O60755 | 1/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etilefrine SCHEMBL29603739 | 0.89 | HIF1A (1.00) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| Etilefrine SCHEMBL150802 | 0.89 | HIF1A (1.00) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| Etilefrine SCHEMBL30510958 | 0.89 | HIF1A (1.00) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| Etilefrine SCHEMBL31204243 | 0.87 | HIF1A (0.97) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| Etilefrine SCHEMBL207591 | 0.87 | HIF1A (0.97) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| Etilefrine SCHEMBL10753730 | 0.78 | HIF1A (0.78) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| Etilefrine SCHEMBL2733170 | 0.78 | HIF1A (0.78) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| SCHEMBL10558292 | 0.76 | HIF1A (0.66) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| SCHEMBL19329764 | 0.74 | HIF1A (0.72) | HIF1ALMNAGALR3ADRB1ADRB2 | |
| SCHEMBL20852549 | 0.74 | HIF1A (0.61) | HIF1ALMNAGALR3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |