Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13445961 | 0.89 | CYP3A4 (0.52) | TSHRCYP3A4HPGDMEN1KMT2A | |
| SCHEMBL776644 | 0.85 | TSHR (0.70) | TSHRCYP3A4HPGDACHEMEN1 | |
| SCHEMBL21582 | 0.82 | TSHR (1.00) | TSHRCYP3A4HPGDACHEMEN1 | |
| SCHEMBL27371282 | 0.82 | TSHR (1.00) | TSHRCYP3A4HPGDACHEMEN1 | |
| SCHEMBL10336991 | 0.82 | TSHR (1.00) | TSHRCYP3A4HPGDACHEMEN1 | |
| SCHEMBL27393883 | 0.82 | TSHR (1.00) | TSHRCYP3A4HPGDACHEMEN1 | |
| SCHEMBL131412 | 0.82 | TSHR (1.00) | TSHRCYP3A4HPGDACHEMEN1 | |
| SCHEMBL17350200 | 0.81 | TSHR (0.64) | TSHRCYP3A4HPGDACHEMEN1 | |
| SCHEMBL9496224 | 0.81 | TSHR (0.64) | TSHRCYP3A4HPGDACHEMEN1 | |
| SCHEMBL8331868 | 0.80 | TSHR (0.95) | TSHRCYP3A4HPGDACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168833-B2 | Schwartz reagents: methods of in situ generation and use | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20070087270-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SOLUTION SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-04-19 | — | — | US | disclosed |
| US-7169511-B2 | Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-1555711-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY CONTAINING THE SAME | Mitsubishi Chemical Corporation (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20050014071-A1 | Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-01-20 | — | — | US | disclosed |