⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186977 | 0.80 | — | — | |
| SCHEMBL6482128 | 0.77 | — | — | |
| SCHEMBL14740958 | 0.73 | — | — | |
| SCHEMBL1442396 | 0.69 | — | — | |
| SCHEMBL28883130 | 0.69 | — | — | |
| SCHEMBL3160423 | 0.69 | — | — | |
| SCHEMBL643818 | 0.65 | — | — | |
| SCHEMBL28326572 | 0.65 | — | — | |
| SCHEMBL9633575 | 0.65 | — | — | |
| SCHEMBL313388 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10175965-A | — | — | None | — | — | JP | disclosed |
| CN-119371411-A | Phenyl fused ring compounds and their use in the central nervous system | 乐普（北京）医疗器械股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-118812505-A | PI5P4K gamma inhibitor compound, pharmaceutical composition, and preparation method and application thereof | 贵州医科大学 | 2024-10-22 | — | — | CN | disclosed |
| CN-112312969-B | 2, 3-dihydrofuro [2,3-b ] pyridine compounds | 伊莱利利公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-108368107-B | Fused heterocyclic compounds as S1P modulators | 艾伯维公司 | 2021-11-26 | — | — | CN | disclosed |
| US-20200055817-A1 | SPIRO-COMPOUNDS AS SIP MODULATORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-20 | — | — | US | disclosed |
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-11 | — | — | US | disclosed |
| EP-3535244-A1 | SPIRO-COMPOUNDS AS S1P MODULATORS | Abbvie Deutschland GmbH & Co. KG (DE) | 2019-09-11 | — | — | EP | disclosed |
| US-10280159-B2 | Fused (hetero)cyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2019-05-07 | — | — | US | disclosed |
| EP-3394050-A1 | FUSED (HETERO)CYCLIC COMPOUNDS AS S1P MODULATORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-10-31 | — | — | EP | disclosed |
| WO-2009050237-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050232-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050234-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009034029-A2 | 1-SUBSTITUTED 4-HETEROCYCLYLPIPERIDINES FOR USE AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009034028-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |
| WO-2008011392-A2 | PROLINE UREA CCR1 ANTAGONISTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES OR INFLAMMATION | LIGAND PHARMACUETICALS INCORPORATED (US) | 2008-01-24 | — | — | WO | disclosed |
| JP-H10175965-A | TETRAHYDROBENZISOXAZOLE DERIVATIVE | SUMITOMO PHARMACEUT CO LTD | 1998-06-30 | — | — | JP | disclosed |
| EP-0002344-A1 | Substituted nitroimidazoles, process for their preparation and compositions containing them | MERCK & CO. INC. (US) | 1979-06-13 | — | — | EP | disclosed |
| US-4144345-A | Dihydroxybenzisoxazolin-3-yl-substituted-5-nitroimidazoles as antibacterials and antiprotozoals | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |