⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28326572 | 0.96 | — | — | |
| SCHEMBL302005 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL8122291 | 0.86 | — | — | |
| Cyclohexanone SCHEMBL28357381 | 0.78 | TRIM24 (0.34) | — | |
| SCHEMBL6482128 | 0.76 | — | — | |
| SCHEMBL2310348 | 0.72 | — | — | |
| SCHEMBL7138226 | 0.72 | — | — | |
| SCHEMBL3160423 | 0.72 | — | — | |
| SCHEMBL186977 | 0.71 | — | — | |
| SCHEMBL31241037 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4681548-B2 | — | — | 2011-05-11 | — | — | JP | claimed |
| JP-2006528163-A | — | — | 2006-12-14 | — | — | JP | claimed |
| EP-1651612-A1 | 3,4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASES (CDK) AND GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MODULATORS | Astex Therapeutics Limited (GB) | 2006-05-03 | — | — | EP | claimed |
| US-7037916-B2 | Pyrimidine derivatives as IL-8 receptor antagonists | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2006-05-02 | — | — | US | claimed |
| WO-2005012256-A1 | 3, 4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASES (CDK) AND GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | claimed |
| WO-2004062609-A2 | PYRIMIDINE DERIVATIVES AS IL-8 RECEPTOR ANTAGONISTS | PHARMACOPEIA, INC. (US) | 2004-07-29 | — | — | WO | claimed |
| US-20040087601-A1 | Pyrimidine derivatives as IL-8 receptor antagonists | PHARMACOPEIA, LLC | 2004-05-06 | — | — | US | claimed |
| JP-7118257-A | — | — | None | — | — | JP | disclosed |
| JP-7179452-A | — | — | None | — | — | JP | disclosed |
| EP-4081210-B1 | PHARMACEUTICAL COMPOSITION OF CASR MODULATORS AND METHODS AND USES THEREOF | LUPIN LTD (IN) | 2026-04-15 | — | — | EP | disclosed |
| US-20260042743-A1 | SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES | COUNCIL SCIENT IND RES (IN) | 2026-02-12 | — | — | US | disclosed |
| US-12447152-B2 | Pharmaceutical combination of PRMT5 inhibitors | LUPIN LIMITED (IN) | 2025-10-21 | — | — | US | disclosed |
| US-12391695-B2 | PRMT5 inhibitors | LUPIN LIMITED (IN) | 2025-08-19 | — | — | US | disclosed |
| US-5585492-A | USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES WHICH ARE MEDIATED BY LTB4 PRODUCTION, SUCH AS PSORIASIS, ULCERATIVE COLITIS, IRRITABLE BOWEL DISEASE AND ASTHMA | G. D. SEARLE & CO. (US) | 1996-12-17 | — | — | US | disclosed |
| WO-1996010999-A2 | LTA4 HYDROLASE INHIBITOR PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | G.D. SEARLE & CO. (US) | 1996-04-18 | — | — | WO | disclosed |
| WO-1996011192-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-04-18 | — | — | WO | disclosed |
| CN-1119189-A | New benzopyran compounds, process for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1996-03-27 | — | — | CN | disclosed |
| JP-H07179452-A | DIHYDROCHROMAN CARBOXYLIC ACIDS AND THEIR PRODUCTION | NIPPON KAYAKU CO LTD | 1995-07-18 | — | — | JP | disclosed |
| JP-H07118257-A | ALDOSE REDUCTASE INHIBITOR | NKK CORP | 1995-05-09 | — | — | JP | disclosed |
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | disclosed |