Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192112 | 0.90 | CYP1A2 (0.62) | CYP1A2SMN1; SMN2RAB9AMAPTGABRA5 | |
| SCHEMBL5264863 | 0.87 | KDM4E (0.53) | CYP1A2SMN1; SMN2RAB9AMAPTGABRA5 | |
| SCHEMBL28577809 | 0.83 | GABRP (0.53) | CYP1A2SMN1; SMN2RAB9AMAPTGABRA2 | |
| SCHEMBL1179292 | 0.81 | CYP1A2 (0.65) | CYP1A2SMN1; SMN2RAB9AMAPTGABRA2 | |
| SCHEMBL23530075 | 0.80 | GABRP (0.62) | CYP1A2SMN1; SMN2RAB9AMAPTGABRA2 | |
| SCHEMBL13933139 | 0.79 | CYP1A2 (0.62) | CYP1A2SMN1; SMN2RAB9AMAPTGABRA2 | |
| SCHEMBL1179778 | 0.78 | CYP1A2 (0.61) | CYP1A2SMN1; SMN2RAB9AMAPTGABRA2 | |
| SCHEMBL19306385 | 0.78 | CYP1A2 (0.61) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL27285116 | 0.77 | CYP1A2 (0.59) | CYP1A2RAB9AMAPTGABRA2GABRB2 | |
| SCHEMBL13853230 | 0.77 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |