SCHEMBL5490478

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5494575	0.73	LCK (1.00)	LCKKDRJAK3MAPK14CTSD
	SCHEMBL5494577	0.73	LCK (0.69)	LCKKDRJAK3MAPK14CTSD
	SCHEMBL5491478	0.73	LCK (0.69)	LCKKDRJAK3MAPK14CTSD
	SCHEMBL4892563	0.73	CCND3 (0.56)	JAK3LMNAMAPK1TSHRCYP2C19
	SCHEMBL15443137	0.73	LRRK2 (0.56)	RAB9AKMT2APTK2
	SCHEMBL25583242	0.73	DDR2 (0.60)	LCKKDRJAK3MAPK14FGFR4
	SCHEMBL5492979	0.72	RIPK2 (0.64)	LCKKDRJAK3MAPK14CTSD
	SCHEMBL5492036	0.72	LCK (0.56)	LCKKDRJAK3MAPK14CTSD
	SCHEMBL14569053	0.72	RIPK2 (0.64)	LCKKDRJAK3MAPK14CTSD
	SCHEMBL14569050	0.72	LCK (0.56)	LCKKDRJAK3MAPK14CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.