Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND3 | P30281 | 2/20 | 0.56 |
| ▸ | CCNK | O75909 | 1/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.56 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.56 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 4/20 | 0.54 |
| ▸ | JAK3 | P52333 | 2/20 | 0.54 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041756 | 0.81 | MYLK4 (0.62) | MYLK4STK17AJAK2MAP4K1MAPK10 | |
| SCHEMBL20516536 | 0.80 | RIPK2 (0.67) | CCND3CCNKCCNA2CDK2CDK9 | |
| SCHEMBL5501445 | 0.79 | MAP4K1 (0.64) | CCND3CCNKCCNA2CDK2CDK9 | |
| SCHEMBL1866937 | 0.79 | MAPT (0.60) | CCND3MYLK4STK17AMAPK1MAPT | |
| SCHEMBL4891700 | 0.78 | CLK4 (0.67) | MAPK1MAPTTP53ALDH1A1LMNA | |
| SCHEMBL3504564 | 0.78 | STK17A (0.58) | CCND3MYLK4STK17AJAK2MAP4K1 | |
| SCHEMBL226380 | 0.78 | STK17A (0.58) | CCND3CCNA2CDK2MYLK4STK17A | |
| SCHEMBL5502267 | 0.78 | RIPK1 (0.70) | JAK3MAPK1ALDH1A1LMNATSHR | |
| SCHEMBL5494435 | 0.78 | MAP4K1 (0.57) | STK17AMAP4K1CDK4CCND1SYK | |
| SCHEMBL5494563 | 0.77 | RIPK1 (0.63) | JAK3MAPK1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311076-A1 | Morpholinylanilinoquinazoline Derivatives For Use As Antiviral Agents | ARROW THERAPEUTICS LIMITED (GB) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311076-A1 | Morpholinylanilinoquinazoline Derivatives For Use As Antiviral Agents | EIF2AK2, MAVS, IRF3 | CCND3 70/4885CCNK 112/4885CCNA2 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.