Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511727 | 0.88 | LMNA (0.32) | LMNA | |
| SCHEMBL4362207 | 0.70 | — | — | |
| SCHEMBL12538032 | 0.69 | TSHR (0.31) | — | |
| Cyclohexane SCHEMBL30181158 | 0.65 | LMNA (0.77) | LMNA | |
| Cyclopentane SCHEMBL29560097 | 0.65 | LMNA (0.77) | LMNA | |
| Cyclopentane SCHEMBL23533982 | 0.65 | LMNA (0.77) | LMNA | |
| Acrylic Acid SCHEMBL8851935 | 0.65 | LMNA (0.77) | LMNA | |
| Acrylic Acid SCHEMBL31202877 | 0.65 | LMNA (0.77) | LMNA | |
| Cyclohexane SCHEMBL29438320 | 0.65 | LMNA (0.77) | LMNA | |
| Acrylic Acid SCHEMBL8513468 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844022-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006071017-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2006-07-06 | — | — | WO | disclosed |