SCHEMBL5490733

SCHEMBL5490733

CCCCCOc1ccc([Si](OC)(OC)OC)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.55
LTA4H P09960 5/20 0.53
CYP2D6 P10635 3/20 0.49
CYP3A4 P08684 2/20 0.49
TP53 P04637 2/20 0.49
TSHR P16473 1/20 0.49
PLA2G4B P0C869 1/20 0.47
NPC1 O15118 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
RAB9A P51151 2/20 0.46
CYP19A1 P11511 1/20 0.46
LMNA P02545 2/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
ALOX15 P16050 1/20 0.45
HSD17B10 Q99714 1/20 0.45
RARB P10826 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27822715 0.98 NR5A1 (0.58) NR5A1LTA4HCYP2D6CYP3A4TP53
SCHEMBL28032455 0.98 NR5A1 (0.58) NR5A1LTA4HCYP2D6CYP3A4TP53
SCHEMBL5490788 0.96 CYP2D6 (0.52) NR5A1LTA4HCYP2D6CYP3A4TSHR
SCHEMBL22259155 0.89 NR5A1 (0.45) NR5A1LTA4HCYP2D6CYP3A4TP53
SCHEMBL27822722 0.84 NR5A1 (0.53) NR5A1LTA4HCYP2D6CYP3A4TP53
SCHEMBL5487181 0.82 NR5A1 (0.56) NR5A1LTA4HCYP2D6CYP3A4TP53
SCHEMBL5484945 0.82 NR5A1 (0.56) NR5A1LTA4HCYP2D6CYP3A4TP53
SCHEMBL27841764 0.82 NR5A1 (0.56) NR5A1LTA4HCYP2D6CYP3A4TP53
SCHEMBL27822732 0.82 NR5A1 (0.56) NR5A1LTA4HCYP2D6CYP3A4TP53
SCHEMBL27822719 0.82 NR5A1 (0.56) NR5A1LTA4HCYP2D6CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103131431-A Display material, liquid crystal alignment agent and liquid crystal display element JSR CORP 2013-06-05 CN disclosed
CN-102591071-A Process for producing liquid crystal display device, the liquid crystal display device, and liquid crystal aligning agent JSR CORP 2012-07-18 CN disclosed
CN-102311739-A The method of manufacture of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CORP 2012-01-11 CN disclosed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed