Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490733 | 0.96 | NR5A1 (0.55) | CYP2D6CYP3A4LTA4HCYP19A1CYP2C9 | |
| SCHEMBL27822715 | 0.94 | NR5A1 (0.58) | CYP2D6CYP3A4LTA4HNR5A1NPC1 | |
| SCHEMBL28032455 | 0.94 | NR5A1 (0.58) | CYP2D6CYP3A4LTA4HNR5A1NPC1 | |
| SCHEMBL22259155 | 0.86 | NR5A1 (0.45) | CYP2D6CYP3A4LTA4HCYP19A1CYP2C9 | |
| SCHEMBL2191110 | 0.83 | NQO1 (0.61) | LTA4HSMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL15208371 | 0.83 | NCF1 (0.45) | CYP2D6CYP3A4CYP2C19CYP1A2SMN1; SMN2 | |
| SCHEMBL26850 | 0.80 | LTA4H (0.70) | CYP2D6CYP3A4LTA4HCYP19A1CYP2C9 | |
| SCHEMBL27822722 | 0.79 | NR5A1 (0.53) | CYP2D6CYP3A4LTA4HCYP2C9CYP2C19 | |
| SCHEMBL10356302 | 0.79 | CYP2D6 (0.55) | CYP2D6CYP3A4LTA4HCYP19A1CYP2C9 | |
| SCHEMBL10357014 | 0.79 | CYP2D6 (0.55) | CYP2D6CYP3A4LTA4HCYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |