SCHEMBL5490744

SCHEMBL5490744

O=Cc1cccc(-c2ccccc2-c2cccc(C=O)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
ALDH1A1 P00352 3/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
CYP2A6 P11509 1/20 0.50
AXL P30530 1/20 0.49
NAT1 P18440 3/20 0.48
BRD4 O60885 1/20 0.46
ELANE P08246 1/20 0.45
UNG P13051 1/20 0.45
CDK8 P49336 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
KDM1A O60341 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
SRC P12931 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13250832 0.96 TRIM24 (0.53) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL29700474 0.88 TRIM24 (0.46) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL14650356 0.88 TRIM24 (0.46) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL4036224 0.86 CYP2A6 (0.52) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL28755065 0.86 TRIM24 (0.49) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL13762175 0.86 KDM1A (0.56) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL5334373 0.86 ALDH1A1 (0.52) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL31491413 0.86 PTPRC (0.47) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL13483001 0.86 PTPRC (0.47) TRIM24TRIM33ALDH1A1CA12CA1
SCHEMBL28538332 0.86 ALDH1A1 (0.52) TRIM24TRIM33ALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573514-B Bridged bisbenzimidazole salt, and preparation method and application thereof 西安交通大学 2023-07-25 CN disclosed
CN-114573514-A Bridged bis-benzimidazole salt and preparation method and application thereof 西安交通大学 2022-06-03 CN disclosed
EP-2559720-A1 CROSSLINKED COMPOSITION Daicel Corporation (JP) 2013-02-20 EP disclosed
JP-2007261991-A METHOD FOR PRODUCING 4,4\"-DIFORMYLTERPHENYLS MITSUBISHI GAS CHEM CO INC 2007-10-11 JP disclosed