Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 17/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1730785 | 0.94 | F2R (0.48) | F2RLMNAKDM4ENPC1MAPT | |
| SCHEMBL14449120 | 0.92 | F2R (0.53) | F2RLMNAKDM4ENPC1MAPT | |
| Bromide SCHEMBL1728702 | 0.91 | F2R (0.54) | F2RLMNAKDM4ENPC1MAPT | |
| Trifluoroacetic Acid SCHEMBL1728797 | 0.91 | F2R (0.46) | F2RKDM4ENPC1MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL1729332 | 0.91 | F2R (0.50) | F2RLMNAKDM4ENPC1MAPT | |
| Bromide SCHEMBL1731777 | 0.91 | F2R (0.49) | F2RLMNAKDM4ENPC1MAPT | |
| SCHEMBL5490772 | 0.90 | F2R (0.47) | F2RLMNAKDM4ENPC1MAPT | |
| Trifluoroacetic Acid SCHEMBL1730591 | 0.90 | F2R (0.49) | F2RLMNAKDM4ENPC1MAPT | |
| Bromide SCHEMBL5486569 | 0.90 | F2R (0.49) | F2RLMNAKDM4ENPC1MAPT | |
| SCHEMBL12151783 | 0.90 | F2R (0.51) | F2RLMNAKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | F2R 2290/4885LMNA 3366/4885KDM4E 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.