Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 17/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730984 | 0.94 | F2R (0.44) | F2RLMNAKDM4ENPC1MAPT | |
| SCHEMBL1728800 | 0.91 | F2R (0.43) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449120 | 0.91 | F2R (0.53) | F2RLMNAKDM4ENPC1MAPT | |
| Trifluoroacetic Acid SCHEMBL5490764 | 0.90 | F2R (0.52) | F2RLMNAKDM4ENPC1MAPT | |
| Bromide SCHEMBL1728702 | 0.90 | F2R (0.54) | F2RLMNAKDM4ENPC1MAPT | |
| SCHEMBL1730594 | 0.90 | F2R (0.46) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL1729334 | 0.90 | F2R (0.47) | F2RLMNAKDM4ENPC1MAPT | |
| SCHEMBL1729559 | 0.89 | F2R (0.40) | F2R | |
| SCHEMBL12151783 | 0.88 | F2R (0.51) | F2RLMNAKDM4ENPC1MAPT | |
| SCHEMBL1729398 | 0.88 | F2R (0.48) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |