Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | MME | P08473 | 6/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 6/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829705 | 1.00 | FOLH1 (0.61) | FOLH1NAALAD2CA1CA2MME | |
| SCHEMBL5851226 | 1.00 | FOLH1 (0.61) | FOLH1NAALAD2CA1CA2MME | |
| Hydrochloric Acid SCHEMBL27515693 | 0.98 | FOLH1 (0.60) | FOLH1NAALAD2CA1CA2MME | |
| Hydrochloric Acid SCHEMBL6653534 | 0.98 | FOLH1 (0.60) | FOLH1NAALAD2CA1CA2MME | |
| SCHEMBL6377128 | 0.87 | FOLH1 (0.58) | FOLH1NAALAD2CA1CA2MME | |
| SCHEMBL5964935 | 0.87 | FOLH1 (0.58) | FOLH1NAALAD2CA1CA2MME | |
| SCHEMBL7275554 | 0.86 | CA2 (0.58) | FOLH1NAALAD2CA1CA2MME | |
| SCHEMBL20578232 | 0.86 | CA2 (0.58) | FOLH1NAALAD2CA1CA2MME | |
| SCHEMBL27167053 | 0.86 | CA2 (0.58) | FOLH1NAALAD2CA1CA2MME | |
| SCHEMBL1012022 | 0.86 | MME (0.63) | NAALAD2CA1CA2MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1376202-A | Stereostructure of decarbamylase and use thereof | KANEGAFUCHI CHEMICAL IND (JP) | 2002-10-23 | — | — | CN | claimed |
| EP-1209234-A1 | STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2002-05-29 | — | — | EP | claimed |
| CN-115772513-A | D-carbamyl hydrolase mutant, gene, expression vector and application thereof | 江南大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-111454933-B | D-carbamoyl hydrolase mutant and application thereof in synthesis of D-aromatic amino acid | 江南大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-111454933-A | D-carbamoyl hydrolase mutant and application thereof in synthesis of D-aromatic amino acid | 江南大学 | 2020-07-28 | — | — | CN | disclosed |
| EP-1616945-B1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI CHEMICAL IND (JP) | 2007-11-21 | — | — | EP | disclosed |
| EP-0801131-B1 | PROCESS FOR PRODUCING D-N-CARBAMOYL-ALPHA-AMINO ACID | KANEGAFUCHI CHEMICAL IND (JP) | 2007-02-21 | — | — | EP | disclosed |
| EP-1616945-A1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2006-01-18 | — | — | EP | disclosed |
| EP-1616946-A1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-20050214912-A1 | Method for producing an optically active amino acid | AJINOMOTO CO., INC. (JP) | 2005-09-29 | — | — | US | disclosed |
| EP-1209234-A1 | STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2002-05-29 | — | — | EP | disclosed |
| EP-0801131-A1 | PROCESS FOR PRODUCING D-N-CARBAMOYL-$g(a)-AMINO ACID | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1997-10-15 | — | — | EP | disclosed |