SCHEMBL5490932

SCHEMBL5490932

FC(F)(F)c1cccc(C[Si](Cl)(Cl)Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.55
IDO1 P14902 2/20 0.53
HTR2A P28223 2/20 0.51
HTR2B P41595 2/20 0.51
HTR2C P28335 1/20 0.51
ACP3 P15309 1/20 0.50
MIF P14174 2/20 0.49
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
GRIN2B Q13224 1/20 0.46
MAOB P27338 3/20 0.45
SIGMAR1 Q99720 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
ADRA2C P18825 1/20 0.45
SLC6A4 P31645 1/20 0.45
ADRA1A P35348 1/20 0.45
DRD3 P35462 1/20 0.45
OPRK1 P41145 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735084 0.81 TAAR1 (0.55) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL4447466 0.79 KMT2A (0.36) TAAR1IDO1KDM4EALDH1A1GRIN2B
SCHEMBL2124661 0.78 TAAR1 (0.56) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL121048 0.78 TAAR1 (0.60) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL29824490 0.78 TAAR1 (0.60) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL3237564 0.77 TAAR1 (0.64) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL5103155 0.77 TAAR1 (0.64) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL15737995 0.77 IDO1 (0.53) TAAR1IDO1HTR2AHTR2BHTR2C
Ammonia Solution, Strong SCHEMBL11220774 0.76 TAAR1 (0.58) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL2906486 0.76 TAAR1 (0.58) TAAR1IDO1HTR2AHTR2BHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10844479-B2 Transparent omniphobic thin film articles UT-BATTELLE, LLC (US) 2020-11-24 US claimed
US-20180171469-A1 TRANSPARENT OMNIPHOBIC THIN FILM ARTICLES UT BATTELLE LLC (US) 2018-06-21 US claimed
US-20150239773-A1 TRANSPARENT OMNIPHOBIC THIN FILM ARTICLES U.S. DEPARTMENT OF ENERGY 2015-08-27 US claimed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed