Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 5/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 5/20 | 0.31 |
| ▸ | MMP8 | P22894 | 4/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514278 | 0.91 | AVPR1B (0.39) | AVPR1BF2KMT2ABMP1MMP8 | |
| SCHEMBL29029482 | 0.81 | KMT2A (0.38) | KMT2A | |
| SCHEMBL28516147 | 0.78 | AVPR1B (0.45) | AVPR1BF2PLGBMP1MMP8 | |
| SCHEMBL28516145 | 0.78 | AVPR1B (0.45) | AVPR1BF2PLGBMP1MMP8 | |
| SCHEMBL29047048 | 0.77 | KMT2A (0.39) | KMT2A | |
| SCHEMBL28514281 | 0.75 | BMP1 (0.37) | AVPR1BF2PLGBMP1MMP8 | |
| SCHEMBL29400128 | 0.75 | AVPR1B (0.43) | AVPR1BF2KMT2AFABP5HTR6 | |
| SCHEMBL27719856 | 0.74 | KMT2A (0.39) | KMT2ABMP1 | |
| SCHEMBL28860152 | 0.73 | AVPR1B (0.39) | AVPR1BF2KMT2APLGBMP1 | |
| SCHEMBL28860154 | 0.73 | AVPR1B (0.39) | AVPR1BF2KMT2APLGBMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858538-A2 | MUCIN HYPERSECRETION INHIBITORS BASED ON THE STRUCTURE OF MANS AND METHODS OF USE | Biomarck Pharmaceuticals, Ltd. (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006078899-A2 | MUCIN HYPERSECRETION INHIBITORS BASED ON THE STRUCTURE OF MANS AND METHODS OF USE | BIOMARCK PHARMACEUTICALS, LTD. (US) | 2006-07-27 | — | — | WO | disclosed |