Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10150695 | 0.95 | MAOA (0.43) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL991815 | 0.90 | TDP1 (0.54) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL17642036 | 0.89 | MAOA (0.38) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL19487377 | 0.89 | MAOA (0.38) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL18257733 | 0.85 | TDP1 (0.65) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL18256745 | 0.85 | TDP1 (0.65) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL5490993 | 0.85 | TDP1 (0.65) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL18866874 | 0.85 | TDP1 (0.49) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL18256747 | 0.85 | TDP1 (0.65) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL18257737 | 0.85 | TDP1 (0.65) | MAOAMAOBTDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163921-B1 | Peptide derivatives and medicinal compositions | NIPPON SHINYAKU CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1275657-A1 | PEPTIDE DERIVATIVES AND MEDICINAL COMPOSITIONS | Nippon Shinyaku Co., Ltd. (JP) | 2003-01-15 | — | — | EP | disclosed |