Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.54 |
| ▸ | DHODH | Q02127 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5421225 | 0.93 | GAA (0.49) | GAAPTGDR2DHODHMEN1KMT2A | |
| SCHEMBL5367089 | 0.92 | GAA (0.62) | GAAPTGDR2DHODHMEN1KMT2A | |
| SCHEMBL5412970 | 0.90 | PTGDR2 (0.62) | GAAPTGDR2MEN1KMT2AKDM4E | |
| SCHEMBL5413651 | 0.89 | PTGDR2 (0.63) | GAAPTGDR2DHODHMEN1KMT2A | |
| SCHEMBL4927025 | 0.88 | MEN1 (0.61) | GAADHODHMEN1KMT2AKDM4E | |
| SCHEMBL5423738 | 0.85 | PTGDR2 (0.54) | GAAPTGDR2MEN1KMT2AKDM4E | |
| SCHEMBL14184689 | 0.82 | MAPT (0.66) | GAAPTGDR2MEN1KMT2AKDM4E | |
| SCHEMBL4923415 | 0.80 | ALDH1A1 (0.71) | GAAPTGDR2MEN1KMT2AKDM4E | |
| SCHEMBL4402426 | 0.79 | GAA (0.69) | GAAPTGDR2DHODHMEN1KMT2A | |
| SCHEMBL5360478 | 0.79 | GAA (0.69) | GAAPTGDR2DHODHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |