SCHEMBL5491763

SCHEMBL5491763

CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)C(=O)NC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.38
ACE P12821 1/20 0.38
CPA1 P15085 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
DPP4 P27487 8/20 0.34
DPP8 Q6V1X1 6/20 0.34
DPP9 Q86TI2 6/20 0.34
TERT O14746 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DPP7 Q9UHL4 5/20 0.31
FAP Q12884 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120715 0.80 MME (0.44) MMEACECPA1ACE2DPP4
SCHEMBL10057901 0.80 MME (0.44) MMEACECPA1ACE2DPP4
SCHEMBL29616849 0.79 DPP4 (0.42) DPP4DPP8DPP9TERTDPP7
SCHEMBL8723093 0.76 MME (0.62) MMEACECPA1ACE2DPP4
SCHEMBL8723097 0.76 MME (0.62) MMEACECPA1ACE2DPP4
SCHEMBL15663557 0.76 MME (0.62) MMEACECPA1ACE2DPP4
SCHEMBL15700570 0.74 ALDH1A1 (0.46) MMEACECPA1ACE2DPP4
SCHEMBL29886647 0.73 MME (0.59) MMEACECPA1ACE2DPP4
SCHEMBL16667894 0.73 BIRC2 (0.42) MMEACECPA1ACE2DPP4
SCHEMBL27343659 0.73 BIRC2 (0.42) MMEACECPA1ACE2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7199103-B2 Synthetic compounds and compositions with enhanced cell binding THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-04-03 US disclosed
US-20050164944-A1 Synthetic compounds and compositions with enhanced cell binding THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2005-07-28 US disclosed
US-6818620-B2 POLYPEPTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-11-16 US disclosed
US-20020037853-A1 Synthetic compounds and compositions with enhanced cell binding THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-03-28 US disclosed
US-6268348-B1 THAT MIMIC THE CONFORMATION NECESSARY FOR RECOGNITION AND DOCKING OF COLLAGEN BINDING SPECIES (SUCH AS CELL SURFACE RECEPTORS FOR COLLAGEN AND FIBRONECTIN) AND HAVE THE AMINO ACID RESIDUES-ILE-ALA-FOLDED IN A BETA-BEND. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2001-07-31 US disclosed
US-5958428-A SYNTHETIC PEPTIDES THAT MIMIC THE CONFORMATION NECESSARY FOR RECOGNITION AND DOCKING OF COLLAGEN BINDING SPECIES (SUCH AS CELL SURFACE RECEPTORS FOR COLLAGEN AND FIBRONECTIN) AND HAVE THE AMINO ACID RESIDUES-ILE-ALA-FOLDED IN A .BETA.-BEND THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-09-28 US disclosed
US-5674848-A PACKING MATERIAL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-10-07 US disclosed
US-5635482-A IMPLANT COMPRISING MATRIX FORMED OF BIOMATERIAL AND PEPTIDE HAVING ENHANCED CELL BINDING WITH RESPECT TO COLLAGEN THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-06-03 US disclosed