Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11610656 | 0.93 | OPRD1 (0.53) | OPRD1SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL10460416 | 0.89 | TDP1 (0.50) | MMP1MMP2MMP3MMP7MMP9 | |
| Hydrochloric Acid SCHEMBL10460896 | 0.86 | TDP1 (0.51) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL5497606 | 0.86 | OPRD1 (0.55) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21381653 | 0.82 | TDP1 (0.44) | SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL21382073 | 0.82 | TDP1 (0.44) | SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL21382050 | 0.82 | TDP1 (0.44) | SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL30149794 | 0.82 | TDP1 (0.44) | SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL21382077 | 0.80 | HTR2C (0.52) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21382309 | 0.80 | HTR2C (0.52) | OPRD1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066259-B1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2007-01-10 | — | — | EP | disclosed |
| US-6440440-B1 | BACTERICIDES, FUNGICIDES, NEMATOCIDES, MITICIDES, INSECTICIDES, AND HERBICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-27 | — | — | US | disclosed |
| EP-1066259-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051578-A1 | BIOCIDAL BENZYLBIPHENYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-10-14 | — | — | WO | disclosed |