Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28150959 | 0.76 | DPP4 (0.49) | DPP4CYP19A1FOLH1PADI4CYP1A1 | |
| SCHEMBL28150958 | 0.76 | DPP4 (0.49) | DPP4CYP19A1FOLH1PADI4CYP1A1 | |
| SCHEMBL5492431 | 0.75 | DPP4 (0.46) | DPP4CYP19A1FOLH1PADI4CYP1A1 | |
| SCHEMBL24233113 | 0.74 | FOLH1 (0.45) | DPP4CYP19A1FOLH1PADI4CYP1A1 | |
| SCHEMBL5499917 | 0.74 | DPP4 (0.44) | DPP4CYP19A1FOLH1PADI4CYP1A1 | |
| SCHEMBL5499057 | 0.74 | DPP4 (0.44) | DPP4CYP19A1FOLH1PADI4CYP1A1 | |
| SCHEMBL14656409 | 0.74 | FOLH1 (0.45) | DPP4CYP19A1FOLH1PADI4CYP1A1 | |
| SCHEMBL14844800 | 0.72 | — | — | |
| SCHEMBL5499916 | 0.72 | DPP4 (0.43) | DPP4CYP19A1FOLH1PADI4CYP1A1 | |
| SCHEMBL27115174 | 0.72 | DPP4 (0.43) | DPP4CYP19A1FOLH1PADI4CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100816-B1 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | BASILEA PHARMACEUTICA AG (CH) | 2007-08-08 | — | — | EP | disclosed |
| EP-1251827-B1 | NASALLY ADMINISTRABLE ANTIFUNGAL CYCLIC PEPTIDE COMPOSITIONS | BASILEA PHARMACEUTICA AG (CH) | 2004-05-26 | — | — | EP | disclosed |
| US-6489440-B1 | Cyclic compounds | BASILEA PHARMACEUTICA AG (CH) | 2002-12-03 | — | — | US | disclosed |