Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492451 | 1.00 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL7849194 | 0.90 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL9381627 | 0.86 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL9191942 | 0.84 | CHRM1 (0.30) | — | |
| SCHEMBL9697773 | 0.84 | — | — | |
| SCHEMBL9198911 | 0.83 | — | — | |
| SCHEMBL9697647 | 0.83 | — | — | |
| SCHEMBL14145046 | 0.82 | CYP1A2 (0.40) | — | |
| SCHEMBL1446403 | 0.82 | CYP1A2 (0.40) | — | |
| SCHEMBL13598441 | 0.82 | CYP1A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265105-B2 | Pyrrolobenzodiazepines | SPIROGEN LIMITED (GB) | 2007-09-04 | — | — | US | disclosed |
| US-20060148788-A1 | Pyrrolobenzodiazepines | SPIROGEN LIMITED (GB) | 2006-07-06 | — | — | US | disclosed |
| CN-1037149-A | The preparation method of 3-alkenyl-1-azabicyclo [3,2,0] hept-2-ene\"-2-carboxylic acid cpd | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-11-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148788-A1 | Pyrrolobenzodiazepines | HCRTR2, MCHR2, CHRM5 | SIGMAR1 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.