Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 18/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5615517 | 0.90 | DPP4 (0.62) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5492467 | 0.90 | DPP4 (0.62) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5489214 | 0.89 | DPP4 (0.63) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL12767534 | 0.86 | DPP4 (0.65) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL1842480 | 0.86 | DPP4 (0.70) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL1842481 | 0.86 | DPP4 (0.70) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8335587 | 0.85 | DPP4 (0.57) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8335584 | 0.84 | DPP4 (0.56) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL3389459 | 0.83 | DPP4 (0.67) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8323766 | 0.83 | DPP4 (0.61) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123470-A1 | Enhancement of growth hormone levels with a dipeptidyl peptidase IV inhibitor and a growth hormone secretagogue | MERCK & CO., INC. | 2007-05-31 | — | — | US | disclosed |
| US-20060052382-A1 | 3-Amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | MERCK & CO., INC. | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052382-A1 | 3-Amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | DPP4, DPP3, DPP7 | DPP4 1/4885DPP8 5/4885DPP7 3/4885 |
| US-20070123470-A1 | Enhancement of growth hormone levels with a dipeptidyl peptidase IV inhibitor and a growth hormone secretagogue | DPP4, DPP3, GHSR | DPP4 1/4885DPP8 6/4885DPP7 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.