Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270755 | 1.00 | CYP1A2 (0.57) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| SCHEMBL4270751 | 1.00 | CYP1A2 (0.57) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| SCHEMBL5489818 | 1.00 | CYP1A2 (0.57) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| Pyrrole SCHEMBL5494858 | 0.93 | CYP1A2 (0.50) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| SCHEMBL5496886 | 0.92 | KDM4E (0.61) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| SCHEMBL5496889 | 0.92 | KDM4E (0.61) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| SCHEMBL5498119 | 0.90 | CYP1A2 (0.54) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| SCHEMBL5498122 | 0.90 | CYP1A2 (0.54) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| Methylpiperazine SCHEMBL5496267 | 0.89 | HPGD (0.52) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 | |
| SCHEMBL5497389 | 0.88 | CYP1A2 (0.46) | CYP1A2HSD17B10TRPM8CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073860-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | claimed |
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | claimed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | claimed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | claimed |
| WO-2006103527-A1 | AROMATIC SUBSTITUTED PENTADIENOIC ACID AMIDE FOR COMBINATION WITH ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-10-05 | — | — | WO | claimed |
| US-9073860-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | disclosed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | disclosed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | disclosed |
| WO-2006103527-A1 | AROMATIC SUBSTITUTED PENTADIENOIC ACID AMIDE FOR COMBINATION WITH ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | DDC, APEH, AADAC | CYP1A2 69/4885HSD17B10 620/4885TRPM8 3450/4885 |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | DDC, APEH, AADAC | CYP1A2 69/4885HSD17B10 620/4885TRPM8 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.