Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866460 | 0.84 | MEN1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL5483049 | 0.84 | MEN1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL8282479 | 0.83 | MEN1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL12975255 | 0.82 | MEN1 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL2188825 | 0.82 | MEN1 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL11553169 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL2868156 | 0.82 | MEN1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL14590977 | 0.81 | MEN1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL847723 | 0.79 | KMT2A (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL8282485 | 0.78 | MEN1 (0.58) | ALDH1A1MEN1KMT2ASMN1; SMN2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161032-B2 | Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof | NIHON NOHYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20060167315-A1 | Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof | NIHON NOHYAKU CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1544193-A1 | SULFONAMIDE DERIVATIVES, INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167315-A1 | Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof | CBR3, CNPY2, STS | ALDH1A1 2875/4885MEN1 2708/4885KMT2A 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.