Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20239037 | 0.78 | TSHR (0.33) | TSHR | |
| SCHEMBL5244719 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL37338 | 0.74 | ALDH1A1 (0.46) | TSHR | |
| Propionic Acid SCHEMBL3844795 | 0.72 | FFAR3 (0.56) | — | |
| SCHEMBL3638600 | 0.71 | ALDH1A1 (0.42) | TSHR | |
| SCHEMBL7083879 | 0.71 | ALDH1A1 (0.42) | TSHR | |
| SCHEMBL1535125 | 0.71 | ALDH1A1 (0.42) | TSHR | |
| Hydrochloric Acid SCHEMBL81805 | 0.71 | ALDH1A1 (0.42) | TSHR | |
| SCHEMBL1267233 | 0.71 | ALDH1A1 (0.42) | TSHR | |
| SCHEMBL5595182 | 0.71 | ALDH1A1 (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253184-B2 | 4-Substituted quinolines as antitumor agents | ASTRAZENECA AB (SE) | 2007-08-07 | — | — | US | disclosed |