Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18676084 | 0.82 | CHRM2 (0.46) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL2048982 | 0.81 | CHRM2 (0.48) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL8481321 | 0.78 | CHRM2 (0.50) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21417607 | 0.77 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3ALDH1A1LMNA | |
| SCHEMBL5180021 | 0.77 | CHRM2 (0.46) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL1146142 | 0.76 | APOBEC3G (0.67) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL5179196 | 0.76 | CHRM2 (0.48) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL1146257 | 0.76 | CHRM2 (0.48) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL515497 | 0.76 | CHRM2 (0.48) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL5179203 | 0.76 | CHRM2 (0.48) | CHRM2SLC6A4SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737815-A1 | THIO-SUBSTITUTED BIARYL-METHANESULFINYL DERIVATIVES | CEPHALON, INC. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100308-A1 | THIO-SUBSTITUTED BIARYL-METHANESULFINYL DERIVATIVES | CEPHALON, INC. (US) | 2005-10-27 | — | — | WO | disclosed |
| WO-1996037469-A1 | N-BENZYLINDOL-3-YL PROPANIC ACID DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1996-11-28 | — | — | WO | disclosed |