SCHEMBL5493456

SCHEMBL5493456

Clc1ccc2c(c1)Oc1c(cc(Cl)c(Cl)c1Cl)O2

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHR P35869 19/20 0.71
FLT1 P17948 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29488625 1.00 AHR (0.71) AHRFLT1
SCHEMBL29623191 1.00 AHR (0.71) AHRFLT1
SCHEMBL9346815 1.00 AHR (0.71) AHRFLT1
SCHEMBL29353294 0.84 AHR (1.00) AHRFLT1
SCHEMBL2885718 0.84 AHR (1.00) AHRFLT1
SCHEMBL2886579 0.82 AHR (0.73) AHRFLT1
SCHEMBL896902 0.82 AHR (1.00) AHRFLT1
SCHEMBL9579657 0.82 AHR (0.86) AHRFLT1
SCHEMBL30118871 0.82 AHR (0.86) AHRFLT1
SCHEMBL5967950 0.82 AHR (0.86) AHRFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251635-B1 Monoclonal antibodies and method for detecting dioxins and dibenzofurans UNIV CALIFORNIA (US) 1994-08-10 EP claimed
US-7279274-B2 Method for diagnosing diabetes in a mammal PRIDE PROTEOMICS A/S (DK) 2007-10-09 US disclosed
US-20060008881-A1 Drug screening; proteins that can be used as targets for the treatment of diabetes SYDDANSK UNIVERSITET (DK) 2006-01-12 US disclosed