Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493588 | 1.00 | SLC7A5 (0.39) | SLC7A5PSMB5DPP4DPP8DPP9 | |
| SCHEMBL5495068 | 0.83 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL5495073 | 0.83 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL29402310 | 0.81 | DPP8 (0.45) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL19105340 | 0.78 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL11915792 | 0.78 | ELANE (0.42) | CA1CA2CA9 | |
| SCHEMBL19105215 | 0.78 | PKM (0.32) | CA1CA2CA9 | |
| SCHEMBL19105406 | 0.77 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL17278283 | 0.75 | SLC7A5 (0.45) | SLC7A5 | |
| SCHEMBL12831909 | 0.74 | PKM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858538-A2 | MUCIN HYPERSECRETION INHIBITORS BASED ON THE STRUCTURE OF MANS AND METHODS OF USE | Biomarck Pharmaceuticals, Ltd. (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006078899-A2 | MUCIN HYPERSECRETION INHIBITORS BASED ON THE STRUCTURE OF MANS AND METHODS OF USE | BIOMARCK PHARMACEUTICALS, LTD. (US) | 2006-07-27 | — | — | WO | disclosed |