Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500303 | 0.85 | KMT2A (0.40) | RORCTHRAKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL308182 | 0.85 | KMT2A (0.39) | RORCTHRAKMT2AMEN1MAPT | |
| SCHEMBL5494187 | 0.72 | F7 (0.46) | MAPTF2F10KDM4E | |
| Hydrochloric Acid SCHEMBL307960 | 0.71 | F7 (0.45) | MAPTF2F10 | |
| SCHEMBL5499067 | 0.70 | F10 (0.42) | F2F10 | |
| Hydrochloric Acid SCHEMBL6544447 | 0.70 | F10 (0.42) | F2F10 | |
| SCHEMBL5497165 | 0.68 | F10 (0.42) | F2F10 | |
| SCHEMBL14628420 | 0.68 | F10 (0.49) | KMT2AF2F10CA12CA1 | |
| SCHEMBL308289 | 0.68 | F10 (0.49) | KMT2AF2F10CA12CA1 | |
| Hydrochloric Acid SCHEMBL6544352 | 0.67 | F10 (0.49) | KMT2AF2F10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453852-B1 | SELECTIVE UROKINASE INHIBITORS | WILEX AG (DE) | 2007-01-17 | — | — | EP | claimed |