Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 9/20 | 0.42 |
| ▸ | F2 | P00734 | 6/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CBS | P35520 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6544343 | 0.99 | HPSE (0.47) | HPSEF7F2F10CASR | |
| SCHEMBL5497144 | 0.93 | F7 (0.42) | F7F2F10NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6544339 | 0.92 | F7 (0.42) | F7F2F10NPC1RAB9A | |
| SCHEMBL5498018 | 0.89 | F7 (0.46) | F7F2F10NPC1RAB9A | |
| SCHEMBL5500799 | 0.89 | NPSR1 (0.51) | F7F2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6543529 | 0.89 | F7 (0.46) | F7F2F10NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6543172 | 0.88 | NPSR1 (0.50) | F7F2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5497090 | 0.85 | F7 (0.43) | F7F2F10MEN1KMT2A | |
| SCHEMBL5493613 | 0.85 | F7 (0.52) | F7F2F10SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6543197 | 0.84 | F7 (0.42) | F7F2F10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453852-B1 | SELECTIVE UROKINASE INHIBITORS | WILEX AG (DE) | 2007-01-17 | — | — | EP | disclosed |
| EP-1453852-A2 | SELECTIVE UROKINASE INHIBITORS | Wilex AG (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003053999-A2 | SELECTIVE ARYLGUANIDINE PEPTIDES AS UROKINASE INHIBITORS | WILEX AG (DE) | 2003-07-03 | — | — | WO | disclosed |