Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6543172 | 0.99 | NPSR1 (0.50) | NPSR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5500284 | 0.93 | KMT2A (0.48) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL6543677 | 0.92 | KMT2A (0.47) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL5497144 | 0.91 | F7 (0.42) | NPSR1RAB9ANPC1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6544339 | 0.90 | F7 (0.42) | NPSR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5493828 | 0.89 | HPSE (0.47) | NPSR1RAB9ANPC1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6544343 | 0.88 | HPSE (0.47) | NPSR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5498018 | 0.85 | F7 (0.46) | NPSR1RAB9ANPC1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6543529 | 0.85 | F7 (0.46) | NPSR1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5497090 | 0.83 | F7 (0.43) | KMT2AMEN1F2F7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453852-B1 | SELECTIVE UROKINASE INHIBITORS | WILEX AG (DE) | 2007-01-17 | — | — | EP | disclosed |