SCHEMBL5493965

SCHEMBL5493965

CCCC[C@@H](C=CC(=O)O)NC(=O)OC(C)(C)C

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSK P43235 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5493959 1.00 CTSK (0.59) CTSK
SCHEMBL2546240 0.91 CTSK (0.48) CTSK
SCHEMBL5468267 0.91 CTSK (0.48) CTSK
SCHEMBL15797176 0.85 CTSK (0.48) CTSK
SCHEMBL9102463 0.85 CTSK (0.48) CTSK
SCHEMBL384990 0.85 CTSK (0.48) CTSK
SCHEMBL384008 0.85 CTSK (0.48) CTSK
SCHEMBL9943895 0.85 CTSK (0.48) CTSK
SCHEMBL3623912 0.82 CTSK (0.78) CTSK
SCHEMBL3285479 0.82 CTSK (0.78) CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490328-A4 COMPOSITIONS AND METHODS FOR INHIBITION OF PHOSPHOLIPASE A2 MEDIATED INFLAMMATION UNIV CALIFORNIA (US) 2007-08-15 EP disclosed
EP-1490328-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF PHOSPHOLIPASE A2 MEDIATED INFLAMMATION The Regents of The University of California (US) 2004-12-29 EP disclosed
WO-2003076389-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF PHOSPHOLIPASE A2 MEDIATED INFLAMMATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-09-18 WO disclosed