Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | AGER | Q15109 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194666 | 0.86 | ADORA2A (0.75) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL4293906 | 0.84 | ADORA2A (1.00) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL4286535 | 0.80 | ADORA2A (0.76) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL8298569 | 0.79 | AGER (0.73) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL4290155 | 0.79 | ADORA2A (1.00) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL4293169 | 0.79 | POLB (0.72) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL5493836 | 0.78 | AGER (0.64) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL16603980 | 0.78 | AGER (1.00) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL4296490 | 0.77 | AGER (0.70) | ADORA2ACYP2C9CYP2C19AGERNPC1 | |
| SCHEMBL4286191 | 0.77 | ADORA2A (1.00) | ADORA2ACYP2C9CYP2C19AGERNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682129-B1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2007-02-21 | — | — | EP | claimed |