Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.63 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049408 | 1.00 | GRIK1 (0.63) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL9306152 | 1.00 | GRIK1 (0.63) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL9306159 | 1.00 | GRIK1 (0.63) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL5494288 | 1.00 | GRIK1 (0.63) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL2754221 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL3824909 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL12099047 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL2229237 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL2754220 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL2754222 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634437-B | Simple preparation method of brivaracetam | 武汉氟本氘合新材料科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-112105621-B | Optically active bridged cyclic secondary amine derivatives | 住友制药株式会社 | 2024-02-20 | — | — | CN | disclosed |
| CN-112771055-B | Optically active bridged piperidine derivatives | 住友制药株式会社 | 2023-10-20 | — | — | CN | disclosed |
| CN-112585140-B | Optically active azabicyclo derivatives | 住友制药株式会社 | 2023-07-04 | — | — | CN | disclosed |
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-113874079-A | Bridged tricyclic carbamoylpyridone compounds and pharmaceutical use thereof | 吉利德科学公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-112771055-A | Optically active bridged piperidine derivatives | 大日本住友制药株式会社 | 2021-05-07 | — | — | CN | disclosed |
| WO-2021060453-A1 | CROSSLINKED OPTICALLY ACTIVE SECONDARY AMINE DERIVATIVE | 大日本住友製薬株式会社 | 2021-04-01 | — | — | WO | disclosed |
| CN-112585140-A | Optically active azabicyclo derivatives | 大日本住友制药株式会社 | 2021-03-30 | — | — | CN | disclosed |
| CN-112105621-A | Optically active bridged cyclic secondary amine derivative | 大日本住友制药株式会社 | 2020-12-18 | — | — | CN | disclosed |
| WO-2020045334-A1 | OPTICALLY ACTIVE AZABICYCLIC DERIVATIVE | 大日本住友製薬株式会社 | 2020-03-05 | — | — | WO | disclosed |
| WO-2020032105-A1 | OPTICALLY ACTIVE BRIDGED PIPERIDINE DERIVATIVE | 大日本住友製薬株式会社 | 2020-02-13 | — | — | WO | disclosed |
| WO-2019189732-A1 | OPTICALLY ACTIVE CROSSLINKED CYCLIC SECONDARY AMINE DERIVATIVE | 大日本住友製薬株式会社 | 2019-10-03 | — | — | WO | disclosed |
| US-20090118382-A1 | Ion Exchange Material, Ion Exchange Column, and Production Method | METROHM AG (CH) | 2009-05-07 | — | — | US | disclosed |
| EP-1737863-A2 | 2-CYANOPYRROLIDINECARBOXAMIDES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | Astellas Pharma Inc. (JP) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005042533-A2 | 2-CYANOPYRROLIDINECARBOXAMIDES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2005-05-12 | — | — | WO | disclosed |
| EP-1043999-A4 | NOVEL SUBSTITUTED PYRIDINE COMPOUNDS USEFUL AS MODULATORS OF ACETYLCHOLINE RECEPTORS | MERCK & CO INC (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-1043999-A1 | NOVEL SUBSTITUTED PYRIDINE COMPOUNDS USEFUL AS MODULATORS OF ACETYLCHOLINE RECEPTORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999032117-A1 | NOVEL SUBSTITUTED PYRIDINE COMPOUNDS USEFUL AS MODULATORS OF ACETYLCHOLINE RECEPTORS | SIBIA NEUROSCIENCES, INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| US-5674905-A | ADMINISTERING AS GASTRIN OR CHOLECYSTOKININ ANTAGONISTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-10-07 | — | — | US | disclosed |