Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.63 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049408 | 1.00 | GRIK1 (0.63) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL9306159 | 1.00 | GRIK1 (0.63) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL5494288 | 1.00 | GRIK1 (0.63) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL5494285 | 1.00 | GRIK1 (0.63) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL2754221 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL3824909 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL12099047 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL2229237 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL2754220 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 | |
| SCHEMBL2754222 | 0.94 | GRIK1 (0.58) | GRIK1GRIK2CA2MAPK1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286904-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1994-02-15 | — | — | US | claimed |
| WO-1988001612-A1 | PROCESSES AND INTERMEDIATES FOR N-(S-3-ALKYL-HEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE | PFIZER INC. (US) | 1988-03-10 | — | — | WO | claimed |
| EP-0258032-A2 | Processes and intermediates for N-(S-3-alkylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1988-03-02 | — | — | EP | claimed |