Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.91 |
| ▸ | CTSK | P43235 | 17/20 | 0.84 |
| ▸ | CTSL | P07711 | 14/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494424 | 1.00 | CTSS (0.91) | CTSSCTSKCTSL | |
| SCHEMBL3018612 | 0.95 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3018606 | 0.95 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3018609 | 0.95 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3020641 | 0.92 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3020639 | 0.92 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3020642 | 0.92 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3018165 | 0.89 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3018173 | 0.89 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3018170 | 0.89 | CTSS (1.00) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658267-A4 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2007-08-01 | — | — | EP | claimed |
| JP-2007502836-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1658267-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2006-05-24 | — | — | EP | claimed |
| WO-2005034848-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2005-04-21 | — | — | WO | claimed |