SCHEMBL5494533

SCHEMBL5494533

Clc1cc(Br)c(Br)c(Br)c1Br

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
APEX1 P27695 1/20 0.40
AHR P35869 4/20 0.36
AKR1B1 P15121 3/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
EIF2AK2 P19525 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31214036 0.79 AHR (0.35) APEX1AHR
SCHEMBL356679 0.75 TDP1 (0.56) TDP1APEX1AHRAKR1B1CA1
SCHEMBL28667897 0.73 TDP1 (0.41) TDP1APEX1AHRAKR1B1CA1
SCHEMBL18686817 0.73 ALDH1A1 (0.45) TDP1APEX1AHRCA1CA2
SCHEMBL3850787 0.72 AHR (0.58) APEX1AHRCA1CA2CSNK2A1
SCHEMBL11281295 0.72 AHR (0.58) APEX1AHRCA1CA2CSNK2A1
SCHEMBL11398028 0.71 HSD17B10 (0.46) TDP1CA1CA2CA4CA6
Ethylene SCHEMBL3851523 0.69 TDP1 (0.50) TDP1APEX1AHRAKR1B1CA1
Ethane SCHEMBL27516377 0.69 TDP1 (0.50) TDP1APEX1AHRAKR1B1CA1
Bromomethane SCHEMBL27669607 0.69 TDP1 (0.50) TDP1APEX1AHRAKR1B1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1246210-B1 Electrical apparatus TOSHIBA LIGHTING & TECHNOLOGY (JP) 2007-10-24 EP claimed
US-6633137-B2 Electrical apparatus TOSHIBA LIGHTING & TECHNOLOGY CORPORATION (JP) 2003-10-14 US claimed
US-20020140368-A1 Electrical apparatus MATSUNAGA YOSHIYUKI (JP) 2002-10-03 US claimed
EP-1246210-A2 Electrical apparatus TOSHIBA LIGHTING & TECHNOLOGY CORPORATION (JP) 2002-10-02 EP claimed
EP-1246210-B1 Electrical apparatus TOSHIBA LIGHTING & TECHNOLOGY (JP) 2007-10-24 EP disclosed
US-6633137-B2 Electrical apparatus TOSHIBA LIGHTING & TECHNOLOGY CORPORATION (JP) 2003-10-14 US disclosed
US-20020140368-A1 Electrical apparatus MATSUNAGA YOSHIYUKI (JP) 2002-10-03 US disclosed
EP-1246210-A2 Electrical apparatus TOSHIBA LIGHTING & TECHNOLOGY CORPORATION (JP) 2002-10-02 EP disclosed