Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.43 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GGH | Q92820 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162038 | 0.81 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLACYP1A2GGH | |
| SCHEMBL162037 | 0.81 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLACYP1A2GGH | |
| SCHEMBL31599178 | 0.81 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLACYP1A2GGH | |
| SCHEMBL180085 | 0.81 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLACYP1A2GGH | |
| SCHEMBL29538289 | 0.79 | FOLH1 (0.53) | FOLH1NAALAD2RIMKLAMEN1ALDH1A1 | |
| SCHEMBL10830382 | 0.79 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLACYP1A2GGH | |
| Hydrochloric Acid SCHEMBL27904743 | 0.79 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLACYP1A2GGH | |
| SCHEMBL28160359 | 0.79 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLACYP1A2GGH | |
| Hydrochloric Acid SCHEMBL5321442 | 0.79 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLACYP1A2GGH | |
| SCHEMBL18575228 | 0.79 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLACYP1A2GGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539183-A4 | THERAPEUTIC TREATMENT METHODS | HOLLIS EDEN PHARMACEUTICALS (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1539183-A1 | THERAPEUTIC TREATMENT METHODS | Hollis-Eden Pharmaceuticals Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2005044279-A1 | PURINE NUCLEOSIDE PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2004019953-A1 | THERAPEUTIC TREATMENT METHODS | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2004-03-11 | — | — | WO | disclosed |
| EP-0938475-A1 | PIPERIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998017647-A1 | PIPERIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 1998-04-30 | — | — | WO | disclosed |